Chlorogenic acid is one of the main antibacterial and antiviral pharmacological components of honeysuckle. The hemihydrate is needle crystal (water). Chlorogenic acid has broad biological activity, and modern science is bioactive for chlorogenic acid. The research has penetrated into many fields such as food, health care, medicine and daily chemicals. The use of weakly polar macroporous adsorption resin to extract chlorogenic acid has high adsorption rate, simple analytical regeneration, and can be reused, and has broad industrial production prospects.