Pure melatonin powder (MT) is one of the hormones secreted by the pineal gland.Melatonin is a kind of indole-heterocyclic compound stored in the body of pine cones. The secretion of melatonin has obvious circadian rhythm, which is inhibited during the day and active at night.Melatonin can inhibit the hypothalamic-pituitary-gonadal axis, reduce the content of gonadotropin releasing hormone, gonadotropin, luteinizing hormone and follicular estrogen, and directly act on the gonadal gland to reduce the content of androgen, estrogen and progesterone.MT has strong neuroendocrine immunomodulatory activity and free radical scavenging antioxidant capacity, which may become a new method and approach of antiviral therapy.